Andarine (S-4)

Advanced SARM for cutting and muscle preservation

€55.00

What’s Included

  • 60 capsules per bottle
  • 25mg pure S4 per capsule
  • 2-month supply (1 cap daily)
  • Third-party lab certificate included

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Product details

Andarine S4 is a powerful selective androgen receptor modulator specifically designed for cutting phases and body recomposition. Known for its exceptional ability to preserve muscle mass while promoting fat loss, S4 is the ideal choice for achieving a lean, defined physique.

Our pharmaceutical-grade Andarine S4 is manufactured under strict quality controls and third-party tested for maximum purity. Each capsule contains 25mg of pure S4, providing optimal cutting support and muscle preservation effects.

Research & Usage Context

Andarine (S-4) has been widely studied for its interaction with androgen receptors and its potential role in influencing body composition. It has been one of the first researched SARMs due to its selective mechanism – it may potentially impact fat loss and muscle building without affecting other tissues and organs.

Because of this profile, Andarine (S-4) is often associated with phases focused on improving overall body composition, especially if maintaining lean tissue while reducing body fat is the main goal. However, it may require further human research to establish the exact potential benefits.

Research & Usage Context

Andarine (S-4) is among the earliest selective androgen receptor modulators to be investigated in scientific research. Its selective interaction with androgen receptors has made it a subject of interest in studies examining muscle tissue, body composition, and related metabolic processes

Thanks to its tissue-selective profile, S-4 Andarine has frequently been explored in research focused on supporting lean muscle while investigating changes in body fat. Although these areas continue to attract scientific attention, additional human studies are still needed to improve the understanding of the compound’s full range of potential applications and effects.

Active Ingredients

Andarine (S4) Selective androgen receptor modulator
25mg
Black Pepper Fruit Extract (Piper nigrum) Enhances absorption and bioavailability
5mg

Purity & Quality

  • Third-party lab tested Third-party lab tested
  • 98.8%+ purity guaranteed 98.8%+ purity guaranteed
  • 24-month shelf life 24-month shelf life

Andarine S4 works by selectively binding to androgen receptors in muscle and bone tissue, promoting anabolic activity while supporting fat oxidation. This dual action makes it particularly effective for cutting phases where maintaining muscle while losing fat is crucial.

The compound increases protein synthesis and prevents muscle catabolism during caloric restriction, while simultaneously enhancing lipolysis and fat burning. S4’s unique properties also improve vascularity and muscle hardness, creating a more defined appearance.

With a half-life of 4-6 hours, Andarine provides consistent support when taken multiple times throughout the day, making it highly effective for cutting goals.

Key Actions

1 Selective muscle tissue targeting
2 Promotes fat oxidation
3 Preserves lean muscle mass

Andarine’s most talked-about side effect is a temporary yellow tint to night vision, which fully resolves once you stop taking it. If you’re new to cutting compounds, our SARMs for Beginners: What to Know Before Your First Cycle is a good place to start.

Real results from real customers

Transformations from verified customers. Individual results vary.

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Reviews

Rated 4.9 by verified UK buyers.

Andarine (S-4)
The strength spike is something different on s4
Chris
Andarine (S-4)
Vision sensitivity was mild and faded, but totally worth it comparing to gains
Bruce
Andarine (S-4)
Body is noticeably harder and drier after 5 weeks
Timothy
Andarine (S-4)
Vision thing is real in the evenings but the muscle hardness and dryness makes it worth it for me at least
Suresh
Andarine (S-4)
Strength honestly came on faster than I expected
Isaac
Andarine (S-4)
Got a bit of yellow tint to my vision but completely worth it comparing to results
Josh
Andarine (S-4)
Didn’t expect such fast delivery
Jerome
Andarine (S-4)
I think this is my favourite one yet
Damian
Andarine (S-4)
Second time taking it, no liver damage or suppression, just fantastic
Francis
Andarine (S-4)
Finally got rid of those 6% of bf
Murray
Andarine (S-4)
God damn I got shredded in no time
Marcin
Andarine (S-4)
I enjoyed the cycle, really got nothing to complain about. Also didnt get any yellow vision side effects everyone was warning me about
Noel
Andarine (S-4)
Best S4 I have tried yet
Zach
Andarine (S-4)
This helped me loss fat very efficently
Grayson
Andarine (S-4)
Best S4 I have tried so far
Glen
Andarine (S-4)
I ran S4 at 25mg per day spilt into two doses (Thinking it would keep the cycle steady). Within the first couple of weeks my muscles looked noticeably drier and strength held up surprisingly good even on a calori deficit. About the famous “Yellow tint” from it, I mean yeah what do yall expect but it wasnt half as bad as everyone describes it. It comes with good benefits, plus once I finished the cycle the tint disappeared.
Oz
Andarine (S-4)
Happy with how things are going with this
Crue
Andarine (S-4)
This is strong but in a good way
John
Andarine (S-4)
This surprised me in a veryy good way
Florentin
Andarine (S-4)
Finally found something I actually enjoy taking
Kade
Andarine (S-4)
Honestly... way better than I thought
Eliott
Andarine (S-4)
why did nobody tell me about this product earlier
Tatton
Andarine (S-4)
Love this. Simple as that
Rikki
Andarine (S-4)
I ran S4 at 25mg per day spilt into two doses (Thinking it would keep the cycle steady). Within the first couple of weeks my muscles looked noticeably drier and strength held up surprisingly good even on a calori deficit. About the famous “Yellow tint” from it, I mean yeah what do yall expect but it wasnt half as bad as everyone describes it. It comes with good benefits, plus once I finished the cycle the tint disappeared.
David
Andarine (S-4)
No side effects
Isaiah
Andarine (S-4)
Better than expected
Aaron
Andarine (S-4)
Funny enough, I lost weight too fast.. Didn't know that was possible ?!
Dominic
Andarine (S-4)
Guys, if you need to cut FAST before fighting then this is best option!
Julian
Andarine (S-4)
Good, works, fast delivery.
Caleb
Andarine (S-4)
Great
Trevor
Andarine (S-4)
Simply the best cutting supplement out there. Amen
Nathan
Andarine (S-4)
Great product, noticed improvements in sleep quality and recovery. Fast shipping and professional packaging.
John
Andarine (S-4)
Within 2 weeks I was lifting heavier than ever. The muscle hardness and definition is unreal. Highly recommended!
David

What are the Key Benefits of Andarine (S-4)?

Enhanced fat loss

Enhanced fat loss

Muscle preservation

Muscle preservation

Improved strength

Improved strength

Better vascularity

Better vascularity

Lean muscle gains

Lean muscle gains

Enhanced recovery

Enhanced recovery

How to Use Andarine (S-4)?

Dosage

Dosage

25mg once daily

Timing

Timing

Take with the morning meal

Cycle Length

Cycle Length

8-12 weeks followed by a 4-week break

Important

Important

Dietary supplement use only

Important Notes

Ideal for cutting phases. Can be split into smaller doses throughout the day for sustained effects.

Training Training

Keep intensity high even in a deficit. Focus on muscle contraction and blood flow through every set.

Diet Diet

Eat at a moderate deficit. Keep protein high to protect muscle, and drink plenty of water, since dehydration worsens Andarine's vision side effect.

Stacking and cycle guidance

Andarine fits well into cutting-focused protocols depending on your research goals. Pick a single companion below to stack with Andarine and save 5%:

Cardarine (GW-501516)

Cardarine (GW-501516) + Andarine (S-4)

Cutting: Cardarine's fat-burning support pairs with Andarine's hard, dry look for a complete cutting stack.

€104.50 €110.00 Save 5%

Andarine 25-50mg each morning. Cardarine 5-10mg, 1-2 hours before training. Run together for 6-8 weeks. PCT required for the Andarine portion.

Ostarine (MK-2866)

Ostarine (MK-2866) + Andarine (S-4)

Cutting: Ostarine adds extra muscle protection alongside Andarine's harder, more vascular look.

€104.50 €110.00 Save 5%

Andarine 25-50mg + Ostarine 15-20mg, both once daily each morning. Run together for 6-8 weeks. PCT required after.

S-23 (SARM)

S-23 (SARM) + Andarine (S-4)

Advanced cutting: S-23 intensifies fat loss and hardening on top of Andarine, built for advanced cutting cycles.

€95.00 €100.00 Save 5%

Andarine 25-50mg + S-23 10-20mg, both once daily each morning. Run together for 6 weeks. PCT mandatory after.

SR9009 (Stenabolic)

SR9009 (Stenabolic) + Andarine (S-4)

Cutting and endurance: SR-9009 adds a metabolic boost that complements Andarine's cutting effect.

€104.50 €110.00 Save 5%

Andarine 25-50mg each morning. SR-9009 10-20mg, split into 2-3 daily doses. Run together for 6-8 weeks. PCT required for the Andarine portion.

Not sure which combo is right for your goal and how to use it properly?

The CORE SARMS Handbook walks through dosing, cycle length, and stacking logic for every compound on this page.

Read the CORE SARMs Handbook →

Post-cycle support

PCT (Post Cycle Therapy)

Recommended after every cycle

PCT (Post Cycle Therapy)

Running any SARM cycle, including Andarine (S-4), temporarily suppresses natural testosterone. Run a PCT protocol after every cycle to restore hormonal balance and protect your gains.

€104.50 €110.00 Save 5%

Andarine causes moderate to strong suppression (50–70%), so PCT is recommended after every cycle. Start your PCT protocol 3 to 5 days after your final dose and run it for 4 weeks to restore hormonal balance before starting again.

Frequently Asked Questions

Andarine S4 is a selective androgen receptor modulator designed for cutting, fat loss, and muscle preservation.

Yes, S4 is excellent for cutting phases as it helps preserve muscle mass while promoting fat loss and improving muscle definition.

While primarily a cutting SARM, S4 can support lean muscle gains, especially when combined with proper nutrition and training.

Users typically experience enhanced fat loss, improved muscle definition, better vascularity, and preserved muscle mass during cuts.

Users have occasionally reported changes in vision, mild fatigue, or hormonal fluctuations. These effects are anecdotal and vary by individual.

Yes, follow recommended cycle lengths with breaks to maintain effectiveness and allow your body to recover.

Andarine (S4) is typically taken once or twice daily due to its shorter half-life of around 4-6 hours. Most users divide their daily dosage into two equal parts, one in the morning and one in the evening, to maintain stable levels in the body. The usual dosage ranges from 25 mg to 50 mg per day, depending on experience and fitness goals. Always start with a lower dose to gauge tolerance and adjust gradually.

For best results, take Andarine S4 at consistent times each day, ideally with meals to improve absorption. If you’re splitting doses, take half in the morning and half in the evening. Consistency is key for maintaining optimal plasma concentration and achieving steady performance and physique gains throughout your cycle.

Andarine (S4) has a half-life of approximately 4-6 hours, meaning it remains active in the body for about 24-36 hours after the last dose. However, complete elimination from the system may take 2-3 days, depending on dosage, frequency, and individual metabolism. Because of its shorter half-life, split dosing is preferred to maintain stable results and reduce fluctuations in energy or vision-related side effects.

The recommended cycle length for Andarine is 8-12 weeks, because the effects are visible gradually. Most users claim that it takes 1-2 weeks to see the initial improvement. The peak impact is reported to occur around the 8th week of the cycle.

Looking for something else?

Is your primary goal muscle strength? Explore other options and see RAD-140 (Testolone) available at CORE SARMS.

Andarine (S-4)

Andarine (S-4)

€55.00